|
Speech Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
<b>Abbreviations:</b> CAS: Childhood Apraxia of Speech; CD: Childhood Dysarthria; DS: Down syndrome; NSA: Normal(ized) Speech Acquisition; PSD: Persistent Speech Delay; PSE: Persistent Speech Errors; SD: Speech Delay; SDCS: Speech Disorders Classification System; SE: Speech Errors; SMD: Speech Motor Delay.
|
31221009 |
2019 |
|
Teratoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In the present study, CAS-positive signals were detected in the normal testicular tissues, cancer adjacent normal testicular tissues, seminoma, yolk sac tumor, and teratoma.
|
31140031 |
2019 |
|
Essential Hypertension
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, the ACE2 variant rs2074192 was associated with EH and EH with CAS ≥50%, while 3 ACE2 variants (rs4240157, rs4646155, and rs4830542) were associated with EH- and hypertension-related AF and left atrial remodeling in south Xinjiang, China.
|
30542083 |
2019 |
|
Acute myocardial infarction
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Aborted cardiac arrest was strongly associated with 2-year mortality in the CAS-AMI group (hazard ratios 13.5, 95% confidence interval 5.34 to 34.15, p <0.001) The incidence of MACE in CAS-AMI patients was significantly lower than in the CAA-AMI group of patients up to 2 years due to the relatively lower rate of repeat revascularization in CAS-AMI patients.
|
31547996 |
2019 |
|
Germ cell tumor
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The current results demonstrated reduced expression of CAS in the human testicular germ cell tumors and the CAS translocation from the nuclear to cytoplasm in seminoma, thereby supporting a possible role in normal testis function and in the development of seminoma.
|
31140031 |
2019 |
|
Lesion of brain
|
0.010 |
Biomarker
|
group |
BEFREE |
Peri-procedural brain lesions prevention in CAS (3PCAS): Randomized trial comparing CGuard™ stent vs. Wallstent™.
|
30266356 |
2019 |
|
Speech Delay
|
0.010 |
Biomarker
|
disease |
BEFREE |
<b>Abbreviations:</b> CAS: Childhood Apraxia of Speech; CD: Childhood Dysarthria; DS: Down syndrome; NSA: Normal(ized) Speech Acquisition; PSD: Persistent Speech Delay; PSE: Persistent Speech Errors; SD: Speech Delay; SDCS: Speech Disorders Classification System; SE: Speech Errors; SMD: Speech Motor Delay.
|
31221009 |
2019 |
|
Deformity
|
0.010 |
Biomarker
|
group |
BEFREE |
Cyanide produced with ethylene by ACS and its incomplete detoxification by β-CAS in mango inflorescence leads to malformation.
|
31797981 |
2019 |
|
Depressed mood
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
The 5-item Mandarin CAS-R was associated with higher levels of self-care maintenance (β = 0.395, P < .001), management (β = 0.219, P < .01), and confidence (β = 0.524, P < .001); perceived social support (β = 0.246, P < .001); and depression (β = -0.125, P < .05).
|
28628499 |
2019 |
|
Adult Teratoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In the present study, CAS-positive signals were detected in the normal testicular tissues, cancer adjacent normal testicular tissues, seminoma, yolk sac tumor, and teratoma.
|
31140031 |
2019 |
|
Mammary Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
We demonstrate a high-grade molecular homology between canine and human CAS, and show that enrichment of upregulated canine CAS genes strongly correlates with the enrichment of an independently derived human stromal signature in the TCGA breast tumour dataset.
|
31308057 |
2019 |
|
Chronic Kidney Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
To evaluate the impact of baseline CKD in TAVR patients only, all patients undergoing an attempted TAVR implant in the US Pivotal Trial and CAS were stratified by baseline eGFR into none/mild, moderate, and severe CKD.
|
30341970 |
2019 |
|
Childhood Teratoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In the present study, CAS-positive signals were detected in the normal testicular tissues, cancer adjacent normal testicular tissues, seminoma, yolk sac tumor, and teratoma.
|
31140031 |
2019 |
|
Multiple Chronic Conditions
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Our objective was to determine the generalizability of the CAS-15 in a multi-institutional fashion.
|
31782808 |
2019 |
|
Adenocarcinoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
We found minimal to absent CAS/CSE1L in all BE tissue samples; however, CAS/CSE1L was upregulated in 60% of LGD and overexpressed in HGD and ADC.
|
27941559 |
2018 |
|
Alzheimer's Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
A better understanding of CAS and their interconnected protein signaling cascade may help provide a treatment for Alzheimer's disease.
|
29789968 |
2018 |
|
Barrett Esophagus
|
0.010 |
Biomarker
|
disease |
BEFREE |
We found minimal to absent CAS/CSE1L in all BE tissue samples; however, CAS/CSE1L was upregulated in 60% of LGD and overexpressed in HGD and ADC.
|
27941559 |
2018 |
|
Coronary Artery Vasospasm
|
0.010 |
Biomarker
|
disease |
BEFREE |
The EAT thickness had an independent relationship with CAS [odds ratio (OR) 1.166, 95% confidence interval (CI) 1.07-1.27, P < 0.001] and coronary vasospasm [OR 1.276, 95% CI 1.14-1.43, P < 0.001] after adjusting for clinical cardiovascular risk factors.
|
28766048 |
2018 |
|
Cytomegalovirus Infections
|
0.010 |
Biomarker
|
group |
BEFREE |
Studies on dynamin function in CMV infection will help us understand the host-virus interaction pathways amenable to targeting by conventional small molecules, as well as by newer generation nucleotide-based therapeutics (e.g., small interfering RNA, CRISPR/CAS gRNA, etc.).
|
30282704 |
2018 |
|
Endometriosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, CAS was down-regulated in EMS, with elevated levels of CD147 and nuclear β-cat.
|
29630856 |
2018 |
|
Muscular fasciculation
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Furthermore, we provide genetic evidence that Cas proteins regulate fasciculation of DRG sensory projections.
|
29662228 |
2018 |
|
Flushing
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
One hundred and sixty-eight male Cobb 500 broiler chicks were used to evaluate the effect of two drying methods (freeze-dryer vs. forced air-oven) and two drying temperatures (40 vs. 55°C) (Exp 1), while ninety-six chicks were used to evaluate the effect of flushing and squeezing as well as marker types (titanium vs. chromium) on apparent ileal DM, N, Ca, P, and AA digestibility (Exp 2).
|
29514296 |
2018 |
|
Osteoporosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Strontium ranelate, a drug approved and until recently used for the treatment of osteoporosis, mediates its effects on bone at least in part via the calcium-sensing (CaS) receptor.
|
29714810 |
2018 |
|
Tuberculosis, Gastrointestinal
|
0.010 |
Biomarker
|
disease |
BEFREE |
'Ancestral' lineages M.bovis (OR-5.22; 95% CI-2.23-8.22, p- < 0.001) and Delhi/CAS (OR-0.57; 95% CI-0.411-0.734, p- < 0.001) were directly associated with lymph node tuberculosis and gastrointestinal tuberculosis (M. bovis-OR-0.33; 95% CI-0.085-0.567, p-0.001 and Delhi/CAS-OR-1.87; 95% CI-1.22-2.53, p- < 0.001) respectively.
|
30587190 |
2018 |
|
Lymph Node Tuberculosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
'Ancestral' lineages M.bovis (OR-5.22; 95% CI-2.23-8.22, p- < 0.001) and Delhi/CAS (OR-0.57; 95% CI-0.411-0.734, p- < 0.001) were directly associated with lymph node tuberculosis and gastrointestinal tuberculosis (M. bovis-OR-0.33; 95% CI-0.085-0.567, p-0.001 and Delhi/CAS-OR-1.87; 95% CI-1.22-2.53, p- < 0.001) respectively.
|
30587190 |
2018 |