|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The expression of CSE1L was detected by immunohistochemistry in seminoma tissues and non-tumour normal testis tissues from patients.
|
30485574 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The combination of CTNB1, XPO2, and CAPG achieved 95% sensitivity and 96% specificity for the discrimination of these subtypes.<b>Conclusions:</b> We developed two uterine aspirate-based signatures to diagnose EC and classify tumors in the most prevalent histologic subtypes.
|
28790116 |
2017 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Furthermore, depletion of CAS by RNAi in the BRAF(V600E)-positive PTC cell line B-CPAP led to reduced tumor cell growth measured by crystal violet assays.
|
26892809 |
2016 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The CAS/imp-α1 transport cycle is linked to XIAP and is required to maintain tumor cell survival in HCC.
|
24799195 |
2014 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Colorectal tumors with K-Ras mutation or high cytoplasmic CSE1L expression were correlated with T status (depth of tumor penetration; P = .004), stage (P = .004), and lymph node metastasis (P = .019).
|
23806821 |
2013 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Immunohistochemistry revealed that CSE1L is upregulated in oligodendroglial tumors.
|
23252729 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
There were significant decreases in both nuclear (p = 0.006) and cytoplasmic (p = 0.003) staining of CSE1L in tumours with lymph node metastasis (stage 3 tumours) compared with lymph node-negative tumours (stage 1 and 2 tumours).
|
22450763 |
2012 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The orally active quinoline-3-carboxamide tasquinimod [ABR-215050; CAS number 254964-60-8), which currently is in a phase II-clinical trial in patients against metastatic prostate cancer, exhibits anti-tumor activity via inhibition of tumor angiogenesis in human and rodent tumors.
|
20470445 |
2010 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Significant reciprocal correlation was observed between high levels of CAS and histologic type, FIGO (International Federation of Obstetrics and Gynecology) stage III and grade 3, residual tumor (>2 cm), 20q13.2 (ZNF217 gene) amplification (>4 copies in >20% cells), and high expression of cyclin D1 (all P < .05).
|
12472286 |
2002 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In neoplastic tissue, CAS was present in 93% of the tumors, Bax in 88%, caspase-3 in 77%, and Bcl-2 in 51%.
|
11603220 |
2001 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Thus, CAS/Crk assembly serves as a "molecular switch" for the induction of cell migration and appears to contribute to the invasive property of tumors.
|
9472046 |
1998 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
For image analysis, Feulgen-stained slides of tumor imprints and of disaggregated tumor cytospin preparations were evaluated with the CAS-200 image analyzer.
|
2047381 |
1991 |