CSF1, colony stimulating factor 1, 1435

N. diseases: 259; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0156372
Disease: Asherman Syndrome
Asherman Syndrome
0.010 AlteredExpression disease BEFREE The CSF1 expression level was reduced in AS patients. 31536655 2020
CUI: C0521585
Disease: Gastrointestinal mucositis
Gastrointestinal mucositis
0.010 AlteredExpression disease BEFREE Salivary levels of CSF-1 and IL-34 did not differ significantly between mucositis and peri-implantitis. 31102043 2020
CUI: C2936258
Disease: Peri-Implantitis
Peri-Implantitis
0.010 AlteredExpression disease BEFREE Salivary levels of CSF-1 and IL-34 did not differ significantly between mucositis and peri-implantitis. 31102043 2020
CUI: C0004604
Disease: Back Pain
Back Pain
0.010 Biomarker phenotype BEFREE Increased colony-stimulating factor 1/colony-stimulating factor 1 receptor signaling is involved in the disc degeneration-induced microglia activation and back pain. 30326776 2019
CUI: C0009319
Disease: Colitis
Colitis
0.010 AlteredExpression disease BEFREE CSF-1 biology is activated in Crohn's disease and in murine T cell transfer colitis. 31710624 2019
CUI: C0027859
Disease: Acoustic Neuroma
Acoustic Neuroma
0.010 AlteredExpression disease BEFREE Immunohistochemical expression of M-CSF and IL-34 was analyzed in ten fast-growing vestibular schwannomas and in ten slow-growing vestibular schwannomas. 30580386 2019
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.010 Biomarker disease BEFREE Association between CSF1 and CSF1R Polymorphisms and Parkinson's Disease in Taiwan. 31554150 2019
CUI: C0152459
Disease: Linear atrophy
Linear atrophy
0.010 Biomarker disease BEFREE Furthermore, <i>Csf1</i><sup><i>op</i>/<i>op</i></sup> mice are deficient in the number of resident macrophages in the spiral ligament and stria vascularis, but not in the spiral ganglion. 31824413 2019
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration
0.010 Biomarker disease BEFREE Increased colony-stimulating factor 1/colony-stimulating factor 1 receptor signaling is involved in the disc degeneration-induced microglia activation and back pain. 30326776 2019
CUI: C0220597
Disease: Adult Hodgkin Lymphoma
Adult Hodgkin Lymphoma
0.010 Biomarker disease BEFREE During characterization of a cDNA library from the Hodgkin lymphoma (HL) cell line L-1236, we discovered a new transcript derived from chromosome 1 at the long intergenic non-protein coding RNA 1768 (LINC01768)/colony stimulating factor 1 (CSF1) region. 31731509 2019
CUI: C0220644
Disease: Childhood Hodgkin Lymphoma
Childhood Hodgkin Lymphoma
0.010 Biomarker disease BEFREE During characterization of a cDNA library from the Hodgkin lymphoma (HL) cell line L-1236, we discovered a new transcript derived from chromosome 1 at the long intergenic non-protein coding RNA 1768 (LINC01768)/colony stimulating factor 1 (CSF1) region. 31731509 2019
Squamous cell carcinoma of esophagus
0.010 Biomarker disease BEFREE Of the remaining 72, 12 biomarkers (FGF19, ST1A1, STAMBP, AXIN1, CASP8, NT3, CD6, CDCP1, CD5, SLAMF1, OPG and CSF1) were associated with increased ESCC risk (p<sub>trend</sub>  < 0.05) with HRs per quantile 1.28-1.65. 31671219 2019
CUI: C0424810
Disease: Periorbital swelling
Periorbital swelling
0.010 Biomarker phenotype BEFREE Preclinical investigations of the CK elevation and periorbital swelling observed after lacnotuzumab administration suggest that these are reversible, nonpathological events linked to inhibition of the CSF-1 pathway. 30894455 2019
Malignant tenosynovial giant cell tumor
0.010 GeneticVariation disease BEFREE The morphologic and immunohistochemical features of these tumors and the presence of CSF1 rearrangements support origin of malignant tenosynovial giant cell tumor from synoviocytes. 30206409 2019
CUI: C1800706
Disease: Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
0.010 Biomarker disease BEFREE We collected explanted lung tissue at the time of lung transplantation from 130 PF-ILD patients (99 (76%) IPF, 14 (11%) SSc-ILD, 17 (13%) other PF-ILD), and wedge biopsies from 200 donor lungs and measured PDGF, FGF, VEGF and M-CSF concentrations by Luminex. 31732480 2019
Central Nervous System Sensitization
0.010 Biomarker disease BEFREE Receptor dependence of BDNF actions in superficial dorsal horn: relation to central sensitization and actions of macrophage colony stimulating factor 1. 30995156 2019
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
0.010 Biomarker disease BEFREE A positive serum and CSF NMDA receptor antibody titer (serum 1:280; CSF 1:8) confirmed the diagnosis of an AIDS-associated anti-NMDA receptor encephalitis; therefore, we treated him with antiretroviral and immunosuppressive therapy. 31768888 2019
CUI: C3495798
Disease: Periodontal inflammation
Periodontal inflammation
0.010 AlteredExpression disease BEFREE The expression of CSF-1 and IL-34 in gingival tissue and fibroblasts suggests involvement in myeloid cell functions during periodontal inflammation.This article is protected by copyright.All rights reserved. 31682007 2019
CUI: C4048329
Disease: Immunosuppression
Immunosuppression
0.010 Biomarker disease BEFREE Based on our analysis, we revealed that the key factors (e.g.WNT5A, TRAIL, CSF1, etc.) mediated the activation of PC-Treg and PC-TAM interaction pathways, which induced the immunosuppression during CRPC progression. 31504033 2019
CUI: C4721414
Disease: Mantle cell lymphoma
Mantle cell lymphoma
0.010 Biomarker disease BEFREE We next demonstrated that BTK inhibition abrogated CSF1 and IL-10 production in MCL cells, leading to the inhibition of macrophage polarization and consequently resulting in the suppression of microenvironment-dependent MCL expansion. 30940906 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.010 Biomarker disease BEFREE These findings revealed that stress-induced elevations in neuronal CSF1 provokes microglia-mediated neuronal remodeling in the medial PFC, contributing to synaptic deficits and development of anxiety- and depressive-like behavior. 28697890 2018
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.010 Biomarker group BEFREE These findings revealed that stress-induced elevations in neuronal CSF1 provokes microglia-mediated neuronal remodeling in the medial PFC, contributing to synaptic deficits and development of anxiety- and depressive-like behavior. 28697890 2018
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome
0.010 Biomarker disease BEFREE M1 and M2 macrophages (Mφ) were differentiated with granulocyte-macrophage colony-stimulating factor or macrophage colony-stimulating factor (M-CSF) from peripheral monocytes of healthy control subjects (HC) and patients with BD. 29895319 2018
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.010 GeneticVariation disease BEFREE The functional rs2050462 in CSF-1 might have a substantial influence on the renal cell carcinoma susceptibility and evolution in the Chinese population. 29734839 2018
CUI: C0007398
Disease: Catatonia
Catatonia
0.010 Biomarker disease BEFREE The inhibitor of CSF1 receptor kinase signaling PLX5622 depleted microglia and alleviated the catatonic symptoms of Cnp mutants. 29252214 2018