LACC1, laccase domain containing 1, 144811

N. diseases: 35; N. variants: 2
Disease: Juvenile arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3495559
Disease: Juvenile arthritis
Juvenile arthritis 		0.140 Biomarker disease BEFREE Our evidences provide further support to the involvement of LACC1/FAMIN deficiency in different types of JIA in addition to the initially described systemic-onset JIA. 30872671 2019
CUI: C3495559
Disease: Juvenile arthritis
Juvenile arthritis 		0.140 GeneticVariation disease BEFREE Genetic variation in the Laccase (multicopper oxidoreductase) domain-containing 1 (LACC1) gene has been shown to affect the risk of Crohn's disease, leprosy and, more recently, ulcerative colitis and juvenile idiopathic arthritis. 27959965 2016
CUI: C3495559
Disease: Juvenile arthritis
Juvenile arthritis 		0.140 GeneticVariation disease BEFREE LACC1 polymorphisms in inflammatory bowel disease and juvenile idiopathic arthritis. 27098602 2016
CUI: C3495559
Disease: Juvenile arthritis
Juvenile arthritis 		0.140 GeneticVariation disease BEFREE Our findings provide strong genetic evidence of an association of a mutation in LACC1 with systemic JIA in the families studied. 25220867 2015
CUI: C3495559
Disease: Juvenile arthritis
Juvenile arthritis 		0.140 Biomarker disease HPO