PWAR1, Prader Willi/Angelman region RNA 1, 145624

N. diseases: 246; N. variants: 0
Disease: leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia 		0.030 Biomarker disease BEFREE Re-expression of PAR-1 in PAR-1-deficient cells combined with a limiting-dilution transplantation assay demonstrated the cell-dose-dependent role of PAR-1 in MLL-AF9 leukemia: PAR-1 inhibited rapid leukemic proliferation when there were a large number of LSCs, while a small number of LSCs required PAR-1 for their efficient growth. 27819671 2017
CUI: C0023418
Disease: leukemia
leukemia 		0.030 Biomarker disease BEFREE Par1-deficiency did not alter initial leukemia development. 24740120 2014
CUI: C0023418
Disease: leukemia
leukemia 		0.030 GeneticVariation disease BEFREE Our ex vivo observations were replicated in human whole blood treated with a PAR1 antagonist. 22187047 2012