PWAR1, Prader Willi/Angelman region RNA 1, 145624

N. diseases: 246; N. variants: 0
Disease: Pulmonary Fibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.030 AlteredExpression disease BEFREE We thus have been suggested that combined inactivation of PAR-1 and PAR-2 would be more effective in blocking pulmonary fibrosis. 25689283 2015
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.030 Biomarker disease BEFREE Stimulation of primary mouse ATII, MLE15 and A549 cells with thrombin (FIIa) - that may activate PAR-1, PAR-3 and PAR-4 - induced epithelial-mesenchymal transition (EMT), a process that has been suggested to be a possible mechanism underlying the expanded (myo)fibroblast pool in lung fibrosis. 23739922 2013
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.030 Biomarker disease BEFREE PAR-1 has been shown to be an important player in the development of pulmonary fibrosis. 17532472 2007