GLIS1, GLIS family zinc finger 1, 148979

N. diseases: 17; N. variants: 5
Disease: Alzheimer's Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.010 Biomarker disease BEFREE Two novel loci associated with Aβ<sub>42</sub> near GLIS1 on 1p32.3 (β = -0.059, P = 2.08 × 10<sup>-8</sup>) and within SERPINB1 on 6p25 (β = -0.025, P = 1.72 × 10<sup>-8</sup>) were also associated with AD risk (GLIS1: OR = 1.105, P = 3.43 × 10<sup>-2</sup>), disease progression (GLIS1: β = 0.277, P = 1.92 × 10<sup>-2</sup>), and age at onset (SERPINB1: β = 0.043, P = 4.62 × 10<sup>-3</sup>). 28247064 2017