IL23R, interleukin 23 receptor, 149233

N. diseases: 306; N. variants: 49
Disease: Tuberculosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 GeneticVariation disease BEFREE The incidence of tuberculosis (TB) remains high among Chinese Uygurs (a long-dwelling ethnic minority in Xinjiang) in China and the variants in IL-23R likely contribute to individual's diversity in host response during infection. 26626589 2015
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 GeneticVariation disease BEFREE A number of models were successfully validated, indicating that interplay between the NRG1 - NRG3, GRIK1 - GRIK3 and IL23R - ATG4C gene pairs may modify susceptibility to TB. 25919455 2014
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 AlteredExpression disease BEFREE Anti-PD-1 antibody enhanced pSTAT3 and IL-23R expression and IL-17 production by M. tb-cultured CD4(+) T cells of tuberculosis patients. 24643836 2014