Disease: Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis 		0.140 Biomarker disease BEFREE In addition, the development of multifarious autoimmune diseases as immune-related adverse events of anti-CTLA-4 and anti-PD-1/PD-L1 therapies and the successful clinical application of the CD28 blocking therapy using CTLA-4-Ig to the treatment of arthritis assure their crucial roles in the regulation of autoimmunity in human. 31758536 2019
CUI: C0003864
Disease: Arthritis
Arthritis 		0.140 Biomarker disease BEFREE Thus, combination CTLA4-Ig and antiviral antibody therapy controls acute CHIKV infection and arthritis and may be a candidate for testing in humans. 28148840 2017
CUI: C0003864
Disease: Arthritis
Arthritis 		0.140 Biomarker disease BEFREE CTLA4-FasL fusion molecule, which has been well characterized in our previous studies for its suppressive effect in rat arthritis model, is chosen as the T-cell antagonist. 23463251 2013
CUI: C0003864
Disease: Arthritis
Arthritis 		0.140 GeneticVariation disease BEFREE Our results suggest that the CTLA-4 gene is involved in predisposition to inflammatory arthropathies in the Northern Irish population. 16248997 2006
CUI: C0003864
Disease: Arthritis
Arthritis 		0.140 Biomarker disease HPO