PLB1, phospholipase B1, 151056

N. diseases: 219; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.050 Biomarker disease BEFREE Exploring calcium ion-dependent effect on the intermolecular interaction between human secreted phospholipase A2 and its peptide inhibitors in coronary artery disease. 31536875 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.050 AlteredExpression disease BEFREE The association of PLA2G2A single nucleotide polymorphisms with type IIa secretory phospholipase A2 level but not its activity in patients with stable coronary heart disease. 25794429 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.050 GeneticVariation disease BEFREE Over the last 10 to 15 years, animal and human observational studies have identified elevated levels of both proinflammatory secretory phospholipase A2-IIA and lipoprotein-associated phospholipase A2 as potential risk factors for coronary heart disease. 26338298 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.050 Biomarker disease BEFREE Type II secretory phospholipase A2 and prognosis in patients with stable coronary heart disease: mendelian randomization study. 21799821 2011
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.050 AlteredExpression disease BEFREE Secretory type II phospholipase A2 is produced and secreted by epicardial adipose tissue and overexpressed in patients with coronary artery disease. 20008021 2010