CTSK, cathepsin K, 1513

N. diseases: 221; N. variants: 36
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.030 AlteredExpression disease BEFREE The aim of the study was to discover the clinicopathological and prognostic implications of cathepsin K (CTSK) expression in oral squamous cell carcinoma. 29618339 2018
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.030 Biomarker disease BEFREE Thus, cathepsin K is implicated not only in protein degradation but also in invasion, migration and adhesion of oral squamous cell carcinomas. 28117540 2017
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.030 AlteredExpression disease BEFREE When cocultured, SCC cells upregulated fibroblastic CTSK expression more potently than did normal keratinocytes, which was mainly attributable to SCC-derived IL-1α. 21146373 2011