CTSK, cathepsin K, 1513

N. diseases: 221; N. variants: 36
Disease: Chondrosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008479
Disease: Chondrosarcoma
Chondrosarcoma 		0.020 Biomarker disease BEFREE The simultaneous upregulation of cathepsins B and L, together with matrix metalloproteinase-13, and the association of cathepsin K with negative prognostic parameters suggests that an aggressive biological behaviour of chondrosarcoma may be related to the synthesis of cysteine proteinases and activation of other proteolytic enzymes. 11223331 2001
CUI: C0008479
Disease: Chondrosarcoma
Chondrosarcoma 		0.020 AlteredExpression disease BEFREE In contrast to chordoma, cathepsin K was not significantly expressed in chorda dorsalis and chondrosarcoma of the skull base. 10923921 2000