CTSK, cathepsin K, 1513

N. diseases: 221; N. variants: 36
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3887524
Disease: Skin Erosion
Skin Erosion
0.020 Biomarker disease BEFREE Although the area of bone erosion was significantly reduced in hTNF-transgenic CK(-/-) mice, the absence of cathepsin K did not completely protect against inflammatory bone lesions. 18240253 2008
CUI: C3887524
Disease: Skin Erosion
Skin Erosion
0.020 AlteredExpression disease BEFREE Of note is the expression of cathepsin K in synovial fibroblasts and mononuclear macrophage-like cells at sites of cartilage erosion in RA and in interdigitating cells of lymphocyte-rich areas. 11920402 2002