CTSZ, cathepsin Z, 1522

N. diseases: 51; N. variants: 4
Disease: Alzheimer's Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.020 AlteredExpression disease BEFREE Taken together, our results implicate systemic LPS administration in ameliorating amyloid pathology in early-to-mid stage disease in the APP<sub>SWE</sub>/PS1<sub>ΔE9</sub> mouse and attract attention to the potential disease involvement of cathepsin Z expressed in CNS myeloid cells in AD. 30459560 2018
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.020 Biomarker disease BEFREE Neuroprotective role of γ-enolase in microglia in a mouse model of Alzheimer's disease is regulated by cathepsin X. 23621429 2013