CYBA, cytochrome b-245 alpha chain, 1535

N. diseases: 177; N. variants: 23
Disease: Diabetes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes 		0.040 Biomarker disease BEFREE The Cox regression model validated four significant variables associated with microalbuminuria: RAGE 374AA (HR 4.19 [1.84-9.58] (p = 0.001)), CYBA TT+TC (HR 2.1 [1.16-3.80], p = 0.015), male sex (HR 1.92 [1.07-3.43], p = 0.028) and diabetes diagnosis at the pediatric stage (HR 1.85 [1.03-3.32], p = 0.039). 26607824 2016
CUI: C0011847
Disease: Diabetes
Diabetes 		0.040 GeneticVariation disease BEFREE The A640G CYBA polymorphism associates with subclinical atherosclerosis in diabetes. 21622150 2011
CUI: C0011847
Disease: Diabetes
Diabetes 		0.040 AlteredExpression disease BEFREE Compared to NGT group, interleukin-6, tumor necrosis factor-alpha (TNF-alpha), p(22)Phox NADPH oxidase, and thioredoxin interacting protein (TXNIP) mRNA levels were higher and suppressor of cytokine signaling (SOCS-3) mRNA was lower in subjects with IGT and diabetes. 19118408 2009
CUI: C0011847
Disease: Diabetes
Diabetes 		0.040 Biomarker disease BEFREE In contrast, HO-1 gene expression was correlated negatively with p22phox, TBARS, PCO, HbA(1c) and diabetes duration. 16759310 2006