CYBB, cytochrome b-245 beta chain, 1536

N. diseases: 343; N. variants: 75
Disease: Left Ventricular Hypertrophy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy 		0.010 Biomarker disease BEFREE LV myocardial protein expressions of inflammation (TNF-α/NF-κβ), apoptosis (mitochondrial-Bax/cleaved caspase-3/PARP), oxidative stress (NOX-1/NOX-2/oxidized protein), fibrosis (Smad3/TGF-β), DNA/mitochondrial damage (γ-H2AX/cytosolic-cytochrome-C) and LV hypertrophy/pressure-overload (β-MHC/BNP) biomarkers were significantly increased in TAC<sup>2</sup> compared to TAC<sup>1</sup> and SC groups, and significantly increased in TAC<sup>1</sup> compared to SC groups (all <i>P</i> < 0.001). 30323866 2018