Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 AlteredExpression disease BEFREE Semi-quantitative RT-PCR was also performed to determine CYP1B1 expression in several OC cell lines. 25516145 2015
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 GeneticVariation disease BEFREE Studies evaluating CYP1B1_Leu432Val polymorphism are required to further elucidate the risk of ovarian cancer with this polymorphism. 23032576 2012
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 Biomarker disease LHGDN CYP1B1 Leu(432) carriers were at increased risk of ovarian cancer, with an adjusted OR of 1.5 (95% confidence interval, 1.1-2.3) compared with Val(432) homozygotes. 17372243 2007
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 Biomarker disease CTD_human CYP1B1 Leu(432) carriers were at increased risk of ovarian cancer, with an adjusted OR of 1.5 (95% confidence interval, 1.1-2.3) compared with Val(432) homozygotes. 17372243 2007
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 GeneticVariation disease BEFREE CYP1B1 Leu(432) carriers were at increased risk of ovarian cancer, with an adjusted OR of 1.5 (95% confidence interval, 1.1-2.3) compared with Val(432) homozygotes. 17372243 2007
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 GeneticVariation disease BEFREE The aim of this study was to investigate the role of CYP1B1*3 polymorphism as a risk factor for ovarian cancer in a Caucasian population. 15255550 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 Biomarker disease LHGDN The aim of this study was to investigate the role of CYP1B1*3 polymorphism as a risk factor for ovarian cancer in a Caucasian population. 15255550 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.350 GeneticVariation disease BEFREE The high-activity Val432 allele of the CYP1B1 gene, which may be linked to oxidative stress through elevated 4-hydroxylated catecholestrogen formation, was associated with an increased risk of ovarian cancer. 11303589 2001