RUNDC3B, RUN domain containing 3B, 154661

N. diseases: 10; N. variants: 4
Disease: Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.010 PosttranslationalModification phenotype BEFREE We hypothesize that the loss of RUNDC3B secondary to aberrant hypermethylation of the early growth response 3 transcription factor binding site results in dysregulated MAPK signalling and carcinogenesis in lymphoid malignancies.© 2015 The Authors. 26011749 2017