ADRB3, adrenoceptor beta 3, 155

N. diseases: 142; N. variants: 8
Disease: Heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure 		0.520 Biomarker disease BEFREE We examined if treatment with the β3 AR agonist mirabegron increases LVEF in patients with HF. 27990717 2017
CUI: C0018801
Disease: Heart failure
Heart failure 		0.520 Biomarker disease RGD Testosterone modulation of cardiac β-adrenergic signals in a rat model of heart failure. 21549119 2011
CUI: C0018801
Disease: Heart failure
Heart failure 		0.520 Biomarker disease BEFREE According to our knowledge, this is the first report about the beta(3)-AR binding in HF. 19120134 2008
CUI: C0018801
Disease: Heart failure
Heart failure 		0.520 Biomarker disease CTD_human The level of beta(3)-adrenoceptor expression in the study groups was significantly higher than the Sham group (P < 0.01). beta(3)-adrenoceptor expression in the Carvedilol group was lower than the Heart Failure Control and Metoprolol groups (P < 0.01). 17440824 2007
CUI: C0018801
Disease: Heart failure
Heart failure 		0.520 Biomarker disease CTD_human If the levels of beta(3)-AR were too high, they might contribute to the loss of cardiac function and be the foundation of the functional degradation of HF. 15009959 2004