Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031117
Disease: Peripheral Neuropathy
Peripheral Neuropathy
0.030 Biomarker group BEFREE CYP3A5 nonexpressor status has been associated with vincristine-induced peripheral neuropathy. 26565076 2016
CUI: C0031117
Disease: Peripheral Neuropathy
Peripheral Neuropathy
0.030 GeneticVariation group BEFREE Seventeen polymorphisms in regulatory and coding regions of genes controlling VCR targets (TUBB1, MAP4, ACTG1 and CAPG) or potentially influencing VCR levels (ABCB1 and CYP3A5) were investigated for an association with peripheral neuropathy and outcome in childhood ALL patients. 25084203 2014
CUI: C0031117
Disease: Peripheral Neuropathy
Peripheral Neuropathy
0.030 GeneticVariation group BEFREE However, patients with the CYP3A4*1B and CYP3A5*3 genotypes had a decreased risk of peripheral neuropathy that was statistically significant on univariate analysis. 12846892 2003