H2BW1, H2B.W histone 1, 158983

N. diseases: 3; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021364
Disease: Male infertility
Male infertility 		0.040 GeneticVariation phenotype BEFREE It is concluded that H2BFWT gene c.-9C>T and c.368A>G polymorphisms might be genetic risk factors for idiopathic male infertility. 28370107 2018
CUI: C0021364
Disease: Male infertility
Male infertility 		0.040 GeneticVariation phenotype BEFREE This study aimed to investigate the association between -9C>T and 368A>G transitions of H2BFWT gene and male infertility through a case-control, meta-analysis, and a bioinformatics approach. 29453813 2018
CUI: C0021364
Disease: Male infertility
Male infertility 		0.040 GeneticVariation phenotype BEFREE These results indicated that the polymorphism -9C>T and 368A>G in H2BFWT gene are associated with male infertility with idiopathic azoospermia or oligozoospermia, suggesting that H2BFWT gene might be contribute to susceptibility to spermatogenesis impairment in Chinese population. 22509975 2012
CUI: C0021364
Disease: Male infertility
Male infertility 		0.040 GeneticVariation phenotype BEFREE Functional polymorphism in H2BFWT-5'UTR is associated with susceptibility to male infertility. 19583817 2009
CUI: C0004509
Disease: Azoospermia
Azoospermia 		0.010 GeneticVariation disease BEFREE These results indicated that the polymorphism -9C>T and 368A>G in H2BFWT gene are associated with male infertility with idiopathic azoospermia or oligozoospermia, suggesting that H2BFWT gene might be contribute to susceptibility to spermatogenesis impairment in Chinese population. 22509975 2012
CUI: C0028960
Disease: Oligospermia
Oligospermia 		0.010 GeneticVariation disease BEFREE These results indicated that the polymorphism -9C>T and 368A>G in H2BFWT gene are associated with male infertility with idiopathic azoospermia or oligozoospermia, suggesting that H2BFWT gene might be contribute to susceptibility to spermatogenesis impairment in Chinese population. 22509975 2012