Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0856727
Disease: Cholesterol gallstones
Cholesterol gallstones
0.010 AlteredExpression disease BEFREE Messenger RNA level of Cyp27A1, encoding the enzyme 27alpha-hydroxylase, the short heterodimer partner and farnesoid X receptor remained unchanged, whereas the mRNA level of Cyp7A1, the rate limiting step of BA synthesis, was increased more than 400% (p < 0.01) in the liver of GS compared to GS-free subjects. 19995447 2009