CD55, CD55 molecule (Cromer blood group), 1604

N. diseases: 187; N. variants: 12
Disease: Muscle damage ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0410158
Disease: Muscle damage
Muscle damage 		0.030 Biomarker phenotype BEFREE In addition, treatment with an inhibitor of RYR (dantrolene) or activation of FoxO (Forkhead box O)/DAF-16 is effective against heat-induced muscle damage. 28576866 2017
CUI: C0410158
Disease: Muscle damage
Muscle damage 		0.030 Biomarker phenotype BEFREE In MG, pathogenic antibodies activate complement-mediated muscle damage and this may be potentiated in some OP-MG cases because of relative deficiency of decay-accelerating factor/CD55. 26632886 2016
CUI: C0410158
Disease: Muscle damage
Muscle damage 		0.030 Biomarker phenotype BEFREE Complement activation in myasthenia gravis (MG) may damage muscle endplate and complement regulatory proteins such as decay-accelerating factor (DAF) or CD55 may be protective. 19675582 2010