DAO, D-amino acid oxidase, 1610

N. diseases: 78; N. variants: 9
Disease: Kyphosis deformity of spine ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022821
Disease: Kyphosis deformity of spine
Kyphosis deformity of spine 		0.010 Biomarker phenotype BEFREE The aim of this study was to characterise the effects of DAOR199W in vivo, using transgenic mice overexpressing DAOR199W.Marked abnormal motor features, e.g. kyphosis, were evident in mice expressing DAOR199W, which were associated with a significant loss (19%) of lumbar spinal cord motor neurons, analysed at 14 months. 29194436 2017