|
CILIARY DYSKINESIA, PRIMARY, 25
|
0.800 |
Biomarker
|
disease |
MGD |
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
|
23872636 |
2013 |
|
CILIARY DYSKINESIA, PRIMARY, 25
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
|
23872636 |
2013 |
|
CILIARY DYSKINESIA, PRIMARY, 25
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
|
|
|
|
CILIARY DYSKINESIA, PRIMARY, 25
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
|
CILIARY DYSKINESIA, PRIMARY, 25
|
0.800 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
CILIARY DYSKINESIA, PRIMARY, 25
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
|
|
|
|
Dyslexia
|
0.500 |
Biomarker
|
disease |
BEFREE |
We examined 4 SNPs located on genes previously associated to dyslexia (KIAA0319, DCDC2, DYX1C1 and FOXP2) and 3 SNPs within genes related to ADHD (COMT, MAOA and DBH) in a cohort of Spanish children (N = 2078) that met the criteria of having one, both or none of these disorders (dyslexia and ADHD).
|
30379906 |
2018 |
|
Dyslexia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Deficits in learning and memory in mice with a mutation of the candidate dyslexia susceptibility gene Dyx1c1.
|
25989970 |
2017 |
|
Dyslexia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Our results do not reveal a migration disorder in the mouse model, adding to the body of evidence available for Dcdc2 and Dyx1c1 that, unlike in the rat in utero knockdown models, the dyslexia-susceptibility candidate mouse homolog genes do not play an evident role in neuronal migration.
|
27510895 |
2017 |
|
Dyslexia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Several candidate genes have been proposed to be implicated in dyslexia susceptibility, such as DYX1C1, ROBO1, KIAA0319, and DCDC2.
|
28074887 |
2017 |
|
Dyslexia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Our results corroborate the emerging role of DCGs in ciliary function and characterize functional noncoding elements, X-box promoter motifs, in DCG promoter regions, which thus can be targeted for mutation screening in dyslexia and ciliopathies associated with these genes.-Tammimies, K., Bieder, A., Lauter, G., Sugiaman-Trapman, D., Torchet, R., Hokkanen, M.-E., Burghoorn, J., Castrén, E., Kere, J., Tapia-Páez, I., Swoboda, P. Ciliary dyslexia candidate genes DYX1C1 and DCDC2 are regulated by Regulatory Factor (RF) X transcription factors through X-box promoter motifs.
|
27451412 |
2016 |
|
Dyslexia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The brain regions were partly overlapping with the previously reported region influenced by polymorphisms in the dyslexia susceptibility genes DYX1C1 and KIAA0319.
|
26400686 |
2015 |
|
Kartagener Syndrome
|
0.500 |
Biomarker
|
disease |
CTD_human |
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
|
23872636 |
2013 |
|
Kartagener Syndrome
|
0.500 |
GermlineCausalMutation
|
disease |
ORPHANET |
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
|
23872636 |
2013 |
|
Dyslexia
|
0.500 |
Biomarker
|
disease |
BEFREE |
DYX1C1 has been associated with dyslexia and neuronal migration in the developing neocortex.
|
23872636 |
2013 |
|
Polynesian Bronchiectasis
|
0.500 |
Biomarker
|
disease |
CTD_human |
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
|
23872636 |
2013 |
|
Polynesian Bronchiectasis
|
0.500 |
GermlineCausalMutation
|
disease |
ORPHANET |
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
|
23872636 |
2013 |
|
Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus
|
0.500 |
GermlineCausalMutation
|
disease |
ORPHANET |
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
|
23872636 |
2013 |
|
Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus
|
0.500 |
Biomarker
|
disease |
CTD_human |
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
|
23872636 |
2013 |
|
Dyslexia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Association of the DYX1C1 dyslexia susceptibility gene with orthography in the Chinese population.
|
23028439 |
2012 |
|
Dyslexia
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
CYP19A1 expression in human brain correlated with the expression of dyslexia susceptibility genes such as DYX1C1 and ROBO1.
|
22426781 |
2012 |
|
Dyslexia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, our results suggested that the 931C > T variant in KIAA0319, but not the -3G > A in DYX1C1, was significantly associated with the risk of dyslexia.
|
23065966 |
2012 |
|
Dyslexia
|
0.500 |
Biomarker
|
disease |
BEFREE |
The dyslexia candidate gene DYX1C1 is a potential marker of poor survival in breast cancer.
|
22375924 |
2012 |
|
Dyslexia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Recent research using animal models and embryonic RNA interference (RNAi) has shown that a subset of the candidate dyslexia risk genes--DYX1C1, ROBO1, DCDC2, KIAA0319--regulate critical parameters of neocortical development, such as neuronal migration.
|
22326444 |
2012 |
|
Dyslexia
|
0.500 |
Biomarker
|
disease |
BEFREE |
We investigated single nucleotide polymorphisms in three genes previously associated with dyslexia and implicated in neuronal migration (DYX1C1, DCDC2, KIAA0319) and white matter volume in a cohort of 76 children and young adults from the general population.
|
22683091 |
2012 |