DAXX, death domain associated protein, 1616

N. diseases: 137; N. variants: 2
Disease: leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia 		0.040 AlteredExpression disease LHGDN Nuclear domain 10 components promyelocytic leukemia protein and hDaxx independently contribute to an intrinsic antiviral defense against human cytomegalovirus infection. 17942542 2008
CUI: C0023418
Disease: leukemia
leukemia 		0.040 Biomarker disease LHGDN Sumoylation of Daxx regulates IFN-induced growth suppression of B lymphocytes and the hormone receptor-mediated transactivation. 16818774 2006
CUI: C0023418
Disease: leukemia
leukemia 		0.040 Biomarker disease LHGDN Promyelocytic leukemia protein (PML) functions as a glucocorticoid receptor co-activator by sequestering Daxx to the PML oncogenic domains (PODs) to enhance its transactivation potential. 12595526 2003
CUI: C0023418
Disease: leukemia
leukemia 		0.040 Biomarker disease LHGDN The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies. 12953102 2003