DCK, deoxycytidine kinase, 1633

N. diseases: 102; N. variants: 6
Disease: Refractory cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0677936
Disease: Refractory cancer
Refractory cancer 		0.010 GeneticVariation phenotype BEFREE We conclude that structural alteration of the coding region of the dCK gene represents one possible mechanism for ara-C resistance in vivo, but, considering the frequency of this event, other mechanisms may play a more important role for clinical resistance to ara-C in patients with AML. 7514246 1994