DEFB1, defensin beta 1, 1672

N. diseases: 177; N. variants: 8
Disease: Celiac Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007570
Disease: Celiac Disease
Celiac Disease 		0.030 AlteredExpression disease BEFREE hBD1 mRNA was significantly lower in patients with active CD compared with patients on diet modification, whereas the mRNA levels of the other three defensins did not differ significantly between the two subgroups. 20128731 2010
CUI: C0007570
Disease: Celiac Disease
Celiac Disease 		0.030 Biomarker disease BEFREE Semiquantitative real-time reverse transcriptase-polymerase chain reaction (PCR) was carried out with gene-specific primers for human beta-defensin 1 to 6 (hBD1 to 6) and human alpha-defensin 5 and 6 (hD5 and 6) in mucosal biopsies of children diagnosed as having CD (n = 11; 4.2-16.2 years) or Hp gastritis (n = 18; 3.2-16.7 years). 20400909 2010
CUI: C0007570
Disease: Celiac Disease
Celiac Disease 		0.030 Biomarker disease BEFREE No evidence of any association of DEFB1 SNPs with the onset of AIDT, CD, and both AITD and CD on T1D patients was evidenced. 19811257 2009