DEFB1, defensin beta 1, 1672
N. diseases: 177; N. variants: 8
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
|---|---|---|---|---|---|---|---|
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0.040 | AlteredExpression | disease | BEFREE | Helicobacter pylori downregulates expression of human β-defensin 1 in the gastric mucosa in a type IV secretion-dependent fashion. | 23870035 | 2013 |
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0.040 | Biomarker | disease | BEFREE | Semiquantitative real-time reverse transcriptase-polymerase chain reaction (PCR) was carried out with gene-specific primers for human beta-defensin 1 to 6 (hBD1 to 6) and human alpha-defensin 5 and 6 (hD5 and 6) in mucosal biopsies of children diagnosed as having CD (n = 11; 4.2-16.2 years) or Hp gastritis (n = 18; 3.2-16.7 years). | 20400909 | 2010 |
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0.040 | Biomarker | disease | BEFREE | Potential role of human beta-defensin 1 in Helicobacter pylori-induced gastritis. | 18991164 | 2009 |
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0.040 | AlteredExpression | disease | BEFREE | Helicobacter pylori had no impact on the gastric expression of HD-5 and HBD-1, whereas HD-6 was increased in the fundus. | 12719455 | 2003 |