|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
CT26 colon cancer cells were treated with 5-FU and oxaliplatin with or without HGF.
|
29374697 |
2018 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In the current paper, three differently shaped Pluronic F-127-modified IONPs (nanocubes, nanoclusters, and nanorods) were compared side by side in three murine tumor models (4T1 breast cancer, B16 melanoma, and CT26 colon cancer).
|
30344459 |
2018 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we evaluated whether three-dimensional (3D) dynamic contrast-enhanced ultrasound (DCE-US) imaging allows assessing early changes in tumor perfusion following antiangiogenic treatment (bevacizumab administered at a dose of 10 mg/kg b.w.), and whether these changes could predict treatment response in colon cancer tumors that either are responsive (LS174T tumors) or none responsive (CT26) to the proposed treatment.
|
28721500 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
To determine the antitumor efficacy, a syngeneic tumor model in BALB/c mice was created using colon cancer CT26.WT cells, and a xenogeneic tumor model was created in nude mice using the human colon cancer SW480 cell line.Mice were treated with schedule 1.
|
28454342 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Transiently transduced CT26 and HT29 colon cancer cells and stably expressing CT26/NIS-cODC cells were prepared.
|
30116045 |
2018 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
A new Flt3L-encoding adenoviral vector (pAdFlt3L) was administered in two approaches in a CT26 colon cancer model in female BALB/c mice.
|
24114287 |
2013 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Murine macrophage Raw264.7 cells expressing an enhanced firefly luciferase (Raw/effluc) and murine colon cancer CT26 cells coexpressing Rluc and mCherry (CT26/Rluc-mCherry, CT26/RM) were established.
|
26992914 |
2016 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
The in vivo capability of 2-14 to sensitize colon cancer cells to TRAIL-induced apoptosis was evaluated in a syngenic colon cancer model in which CT26-derived grafts were induced in mice.
|
21817114 |
2011 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
These Pt(IV) complexes showed comparable activity, of 2 orders of magnitude higher than reference drug oxaliplatin on three human (HCT 116, SW480, and HT-29) and one mouse (CT26) colon cancer cell lines.
|
30879295 |
2019 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Finally, Rhox5 knockdown by small hairpin RNA (shRNA) in CT26 colon cancer decreased cell proliferation and migration in vitro and tumor growth in vivo .
|
21609483 |
2011 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to investigate the effects of catalpol on the proliferation, growth, invasion, tumor angiogenesis and inflammation of CT26 colon cancer in vitro and in vivo.
|
28826099 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Oral vaccination of T-MPs generated potent inhibitory effect against the growth of B16 melanoma and CT26 colon cancer in mice, which required both T cell and DC activation.
|
28405506 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Bmal1/BMAL1 regulation of rhythmic Mrp2/MRP2 expression was also confirmed in the colon cancer CT26 and Caco-2 cells.
|
31244920 |
2019 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, intraperitoneal application of OXA/TA NPs-H restricted the growth of CT26 peritoneal colon cancer in vivo, improved the quality of life and prolonged the survival time of the model mice.
|
30553061 |
2019 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In vitro, the CT26 and MC38 murine colon cancer cell lines were shown to upregulate IDO expression following stimulation with interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α).
|
30824815 |
2019 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In the current study, bone marrow‑derived dendritic cells from BALB/c mice and undifferentiated murine colon carcinoma CT26.WT cells were used as a cellular model to study the primary role of HMGB1 in colon cancer immunity.
|
29257231 |
2018 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Treating mice bearing CT26 mouse colon cancer tumors with both silibinin and radiation stimulated tumor regression more than radiation alone.
|
29050211 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, immunomodulatory strategies to boost the antitumor immune response induced by DaRT, and the response specificity, were investigated in the colon cancer CT26 mouse model.
|
31637474 |
2019 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, we revealed that the serpin Spn4 from Drosophila melanogaster inhibits the activity of all the PCs found in the constitutive secretory pathway and represses the metastatic potential of the colon cancer cells HT-29 and CT-26.
|
24961901 |
2014 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Cell-Based IL-15:IL-15Rα Secreting Vaccine as an Effective Therapy for CT26 Colon Cancer in Mice.
|
31760731 |
2019 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
We transduced the interleukin-2 (IL-2) gene into murine fibroblasts BALBCL7 or murine colon cancer CT26 using a retroviral vector.
|
10551331 |
1999 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
To extend these in vitro findings, we have obtained mouse colon cancer MC38- and CT26-MEKi resistant syngeneic models (MC38-MR and CT26-MR).
|
31842958 |
2019 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Different groups of CT26 mouse colon cancer cell line received various treatments of cisplatin, ACA, and AA nanocomplexes and then the samples were prepared for Z-scan studies.
|
31362112 |
2019 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In the highly metastatic CT26 murine colon cancer cell line, which expresses endogenous TrkC, silencing TrkC expression by small interfering RNA significantly enhanced BMP-2-induced Smad1 phosphorylation and restored BMP-2 growth inhibitory activity.
|
17942918 |
2007 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Collectively, CPT inhibited the growth, invasion, inflammation and angiogenesis in CT26 colon cancer, and at least partly, by regulating the PI3K/Akt/mTOR signaling and the nuclear translocation of HIF-1α.
|
30388517 |
2018 |