|
Malignant tumor of colon
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In the B16 (H-2b, melanoma) and CT26 (H-2d, colon cancer) murine models, injection of AdmCD40L into established subcutaneous tumors resulted in sustained tumor regression and tumor-free status in >60% of animals.
|
10365667 |
1999 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
We transduced the interleukin-2 (IL-2) gene into murine fibroblasts BALBCL7 or murine colon cancer CT26 using a retroviral vector.
|
10551331 |
1999 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we investigated the antitumor effect of in vivo gene transfer of CD40L to tumor cells using an adenoviral vector (AdCMVmCD40L) in a murine CT-26 colon cancer model.
|
11001366 |
2000 |
|
Malignant tumor of colon
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The extract showed high in vitro anti-tumor activity against human colon cancer cell line CT26 with the IRs ranging from 62 to 89%.
|
17227700 |
2007 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
To evaluate the clinical efficacy of monoclonal antibody (mAb) 3E10 Fv antibody-mediated p53 protein therapy, an Fv-p53 fusion protein produced in Pichia pastoris was tested on CT26.CL25 colon cancer cells in vitro and in vivo in a mouse model of colon cancer metastasis to the liver.
|
17308119 |
2007 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
We also used Foxm1 small interfering RNA-depleted human DLD1 and mouse CT26 colon cancer cell lines to examine DNA replication and anchorage-independent growth.
|
17408638 |
2007 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In the highly metastatic CT26 murine colon cancer cell line, which expresses endogenous TrkC, silencing TrkC expression by small interfering RNA significantly enhanced BMP-2-induced Smad1 phosphorylation and restored BMP-2 growth inhibitory activity.
|
17942918 |
2007 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Various doses of I-131 (75, 300, 600, 1,200, and 2,400 microCi/5 mL) were incubated with hNIS-expressing colon cancer (CT26/hNIS) and parental cells (CT26), and numbers of MHC class I and Fas-expressing cells were determined by fluorescence-activated cell sorting (FACS).
|
20053774 |
2010 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Finally, Rhox5 knockdown by small hairpin RNA (shRNA) in CT26 colon cancer decreased cell proliferation and migration in vitro and tumor growth in vivo .
|
21609483 |
2011 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
The in vivo capability of 2-14 to sensitize colon cancer cells to TRAIL-induced apoptosis was evaluated in a syngenic colon cancer model in which CT26-derived grafts were induced in mice.
|
21817114 |
2011 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Subtumoural insertion of the GEM-PU-PL12% membrane more efficiently inhibited the growth of CT-26 colon cancer than other membranes.
|
22366483 |
2012 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Adenovirus-mediated TIMP3 transduction in CT26 colon cancer model demonstrated multiple effects to arrest cancer cell growth and induced massive apoptosis.
|
23037807 |
2012 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
A new Flt3L-encoding adenoviral vector (pAdFlt3L) was administered in two approaches in a CT26 colon cancer model in female BALB/c mice.
|
24114287 |
2013 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, we revealed that the serpin Spn4 from Drosophila melanogaster inhibits the activity of all the PCs found in the constitutive secretory pathway and represses the metastatic potential of the colon cancer cells HT-29 and CT-26.
|
24961901 |
2014 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Imatinib Inhibits the Renewal and Tumorigenicity of CT-26 Colon Cancer Cells after Cytoreductive Treatment with Doxorubicin.
|
26956644 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Murine macrophage Raw264.7 cells expressing an enhanced firefly luciferase (Raw/effluc) and murine colon cancer CT26 cells coexpressing Rluc and mCherry (CT26/Rluc-mCherry, CT26/RM) were established.
|
26992914 |
2016 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, transfection of VP3 and silencing of CD147 genes was achieved through the treatment of tumors with pVIVO1-GFP/VP3 (VP3), psiRNA-CD147/2 (shCD147/2), and their combination of CT26 colon cancer cell-induced in mice.
|
27411985 |
2016 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
MATERIAL AND METHODS We evaluated the expression of TNF-α in 108 human colon cancer tissue samples and 2 colon cancer cell lines (CT26 and HCT116), and analyzed its prognostic values.
|
28190020 |
2017 |
|
Malignant tumor of colon
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In contrast to CORM-3 and 2, a significantly reduced tumor growth was observed with 4 in the murine colon cancer CT-26 model in vivo.
|
28207024 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
The resultant IL-12 induced chondrogenic cells were irradiated with x-ray and inoculated into mice bearing CT26 colon cancer.
|
28231722 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Oral vaccination of T-MPs generated potent inhibitory effect against the growth of B16 melanoma and CT26 colon cancer in mice, which required both T cell and DC activation.
|
28405506 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
To determine the antitumor efficacy, a syngeneic tumor model in BALB/c mice was created using colon cancer CT26.WT cells, and a xenogeneic tumor model was created in nude mice using the human colon cancer SW480 cell line.Mice were treated with schedule 1.
|
28454342 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
Linoleic acid (LA; C-18, n-6 unsaturated fatty acid) and elaidic acid (EA; C-18, trans acid), both known to affect colon carcinogenesis and cancer progression, were administered by gavage to BALB/c mice, which were inoculated with CT26 syngeneic colon cancer cells in the back.
|
28486225 |
2017 |
|
Malignant tumor of colon
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Calcium electroporation induces tumor eradication, long-lasting immunity and cytokine responses in the CT26 colon cancer mouse model.
|
28638724 |
2017 |
|
Malignant tumor of colon
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we evaluated whether three-dimensional (3D) dynamic contrast-enhanced ultrasound (DCE-US) imaging allows assessing early changes in tumor perfusion following antiangiogenic treatment (bevacizumab administered at a dose of 10 mg/kg b.w.), and whether these changes could predict treatment response in colon cancer tumors that either are responsive (LS174T tumors) or none responsive (CT26) to the proposed treatment.
|
28721500 |
2017 |