NQO1, NAD(P)H quinone dehydrogenase 1, 1728

N. diseases: 368; N. variants: 8
Disease: Heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure 		0.020 AlteredExpression disease BEFREE This mechanism is involved in the regulation of cardiac hypertrophy (CH), an antecedent condition to HF where NQO1 downregulation stems from the loss of the distal-specific transcript. 31598705 2019
CUI: C0018801
Disease: Heart failure
Heart failure 		0.020 Biomarker disease BEFREE Thus, modulation of NAD<sup>+</sup>/NADH by NQO1 may be a novel therapeutic approach to prevent chemotherapy-associated heart failure, including AIC. 30291911 2018