NQO1, NAD(P)H quinone dehydrogenase 1, 1728

N. diseases: 368; N. variants: 8
Disease: Liver diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023895
Disease: Liver diseases
Liver diseases 		0.310 AlteredExpression group BEFREE Different expression pattern of Nrf2 regulated genes in end-stage liver disease samples were observed: glutamate-cysteine ligase (GCLC) and glutathione-S-transferase A1 (GSTA1) were significantly down-regulated in most liver disease groups, whereas heme oxidase 1 (HMOX1) and NAD(P)H dehydrogenase [quinone] 1 (NQO1) were not significantly suppressed. 22459801 2012
CUI: C0023895
Disease: Liver diseases
Liver diseases 		0.310 Biomarker group CTD_human The expression of NAD(P)H:quinone oxidoreductase 1 is high in human adipose tissue, reduced by weight loss, and correlates with adiposity, insulin sensitivity, and markers of liver dysfunction. 17405841 2007
CUI: C0023895
Disease: Liver diseases
Liver diseases 		0.310 Biomarker group CTD_human NQO1 activity was determined in cytosol from normal, APAP and PBC liver specimens. 16610002 2006