DLX5, distal-less homeobox 5, 1749

N. diseases: 69; N. variants: 4
Disease: T-Cell Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma 		0.030 Biomarker disease BEFREE Integrated ChIP-seq and mRNA microarray analyses identified Notch1/3 and Irs2 as direct transcriptional targets of Dlx5, a gene signature unique to lymphomas from Lck-Dlx5 mice as compared to T-cell lymphomas from Lck-MyrAkt2 mice, which were previously reported by our group. 28122332 2017
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma 		0.030 AlteredExpression disease BEFREE We had previously found that Dlx5 is overexpressed in an Akt2 transgenic model of T-cell lymphoma. 21045156 2010
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma 		0.030 GeneticVariation disease BEFREE A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice. 18316591 2008