DMPK, DM1 protein kinase, 1760

N. diseases: 96; N. variants: 3
Disease: Hypogonadism ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020619
Disease: Hypogonadism
Hypogonadism 		0.120 AlteredExpression disease BEFREE The DMPK gene expression is pleiotropic and includes the premature expression of several age-related signs, symptoms and metabolic disturbances including hormonal dysfunctions, progressive decrease in muscular mass, presenile cataracts, alopecia, reduced alertness, insulin resistance, dyslipidemia, erectile dysfunction and hypogonadism. 12630069 2002
CUI: C0020619
Disease: Hypogonadism
Hypogonadism 		0.120 GeneticVariation disease BEFREE We found a significant correlation (p < 0.001) between CTG repeat size and levels of both LH and FSH: these findings suggest that the severity of hypogonadism is related to MT-PK gene mutation. 8077624 1994
CUI: C0020619
Disease: Hypogonadism
Hypogonadism 		0.120 Biomarker disease HPO