DNASE1, deoxyribonuclease 1, 1773

N. diseases: 180; N. variants: 8
Disease: Secondary malignant neoplasm of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0153676
Disease: Secondary malignant neoplasm of lung
Secondary malignant neoplasm of lung 		0.020 Biomarker disease BEFREE Roles of neutrophils in O<sub>3</sub>-induced lung metastasis were highlighted using blocking anti-Ly6G antibodies; moreover, the implication of neutrophil extracellular traps (NETs) in metastatic processes was evaluated using <i>MRP8cre-Pad4lox/lox</i> mice or by treating mice with DNase I. 31142617 2019
CUI: C0153676
Disease: Secondary malignant neoplasm of lung
Secondary malignant neoplasm of lung 		0.020 Biomarker disease BEFREE In agreement with previous reports, the NETosis inhibitor DNase I inhibited lung metastasis of 4T1 cells. 27960041 2017