DNASE1L3, deoxyribonuclease 1 like 3, 1776

N. diseases: 126; N. variants: 4
Disease: Hepatocellular necrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1855038
Disease: Hepatocellular necrosis
Hepatocellular necrosis 		0.010 Biomarker phenotype BEFREE We found that (i) DNase1L3 was the endonuclease responsible for generating cfDNA in acetaminophen-induced hepatocyte necrosis and (ii) CAD and DNase1L3 cooperated in producing cfDNA for anti-Fas mediated hepatocyte apoptosis. 31255286 2019