Depressive disorder
|
0.500 |
Biomarker
|
disease |
BEFREE |
Candidate gene study reveals DRD1 and DRD2 as putative interacting risk factors for youth depression.
|
27472173 |
2016 |
Depressive disorder
|
0.500 |
Biomarker
|
disease |
PSYGENET |
Findings for DAT1 intron8 were also significant for two EMD subscales, generalized anxiety (ηp(2)=.065) and depression (ηp(2)=.059), and for DRD2 rs2283265, depression (ηp(2)=.053).
|
24780147 |
2014 |
Depressive disorder
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Findings for DAT1 intron8 were also significant for two EMD subscales, generalized anxiety (ηp(2)=.065) and depression (ηp(2)=.059), and for DRD2 rs2283265, depression (ηp(2)=.053).
|
24780147 |
2014 |
Depressive disorder
|
0.500 |
Biomarker
|
disease |
PSYGENET |
Molecular genetic studies point to potential risk loci of psychotic depression shared with schizoaffective disorder (1q42, 22q11, 19p13), depression, bipolar disorder, and schizophrenia (6p, 8p22, 10p13-12, 10p14, 13q13-14, 13q32, 18p, 22q11-13) and several vulnerability genes possibly contributing to an increased risk of psychotic symptoms in depression (eg, BDNF, DBH, DTNBP1, DRD2, DRD4, GSK-3beta, MAO-A).
|
23512949 |
2013 |
Depressive disorder
|
0.500 |
Biomarker
|
disease |
PSYGENET |
The A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D(2/3) receptor binding in healthy individuals (Con) as well as depression and addiction.
|
23683269 |
2013 |
Depressive disorder
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D(2/3) receptor binding in healthy individuals (Con) as well as depression and addiction.
|
23683269 |
2013 |
Depressive disorder
|
0.500 |
Biomarker
|
disease |
PSYGENET |
Association between DRD2/ANKK1 Taq1A genotypes, depression and smoking cessation with nicotine replacement therapy.
|
21540761 |
2011 |
Depressive disorder
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Research implicates the A1 allele of the dopamine D2 receptor gene (DRD2) Taq1A polymorphism in the development of depression and anxiety.
|
20526230 |
2010 |
Depressive disorder
|
0.500 |
Biomarker
|
disease |
PSYGENET |
Research implicates the A1 allele of the dopamine D2 receptor gene (DRD2) Taq1A polymorphism in the development of depression and anxiety.
|
20526230 |
2010 |
Depressive disorder
|
0.500 |
Biomarker
|
disease |
BEFREE |
The present study builds off this literature and examines whether DRD2 moderates the effect of violent victimization on depression.
|
18501970 |
2009 |
Depressive disorder
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
It was found that the combination of COMT Met allele and DRD2 T allele predicted more severe depression in those already affected but did not predict the risk of depression when compared to normal population.
|
18929622 |
2008 |
Depressive disorder
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
A number of studies suggest that variants in dopamine receptor genes, such as DRD2, are associated with depression but it is unclear if such variants also modify the association between life events and depression.
|
17585060 |
2007 |
Depressive disorder
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Subjects with the DRD2 Al allele compared to those without this allele had significantly higher scores on GHQ 2 (anxiety/insomnia), GHQ 3 (social dysfunction) and GHQ 4 (depression).
|
16632165 |
2006 |
Depressive disorder
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Individuals high in trait depression or nicotine dependence or with at least one dopamine D(2) receptor A1 allele experienced greater EEG deactivation following abstinence, especially in the right hemisphere during the stressful task.
|
15203798 |
2004 |
Depressive disorder
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Before paroxetine treatment, patients with the DRD2 A1+ allele (A1A2 genotype) compared to those with the A1- allele (A2A2 genotype) had higher total GHQ psychopathological scores (P=0.040) and higher GHQ subscale scores for anxiety/insomnia (0.046), social dysfunction (P=0.033) and depression (P=0.011).
|
12957328 |
2003 |
Depressive disorder
|
0.500 |
Biomarker
|
disease |
BEFREE |
Earlier findings concerning association of DRD2 E8 A/A with increased anxiety and depression are replicated for the first time.
|
11692072 |
2001 |
Depressive disorder
|
0.500 |
Biomarker
|
disease |
HPO |
|
|
|