DRD2, dopamine receptor D2, 1813

N. diseases: 437; N. variants: 42
Disease: Psychotic symptom ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0871189
Disease: Psychotic symptom
Psychotic symptom 		0.030 AlteredExpression phenotype BEFREE Furthermore several cortical regions showing higher clusters of DRD2 expressing neurons are involved in the regulation of emotional, cognitive and sensory functions that can be involved in the expression of psychotic symptoms. 30528973 2019
CUI: C0871189
Disease: Psychotic symptom
Psychotic symptom 		0.030 Biomarker phenotype BEFREE Dopamine D2-receptor blockade by antipsychotic medication reduces psychotic symptoms, but may reduce subjective well-being. 28542034 2017
CUI: C0871189
Disease: Psychotic symptom
Psychotic symptom 		0.030 GeneticVariation phenotype BEFREE One significant association was found in the unipolar group: dopamine D2 receptor promoter allele 2 with history of psychotic symptoms, P = 0.0165. 10686549 2000