DRD3, dopamine receptor D3, 1814

N. diseases: 199; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 GeneticVariation disease BEFREE The Association between DRD3 Ser9Gly Polymorphism and Depression Severity in Parkinson's Disease. 31143436 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 Biomarker disease BEFREE The aim of the present study was to examine the role of DRD3 in the anxiety-like and depression-like behavioral changes induced by estrogen and progesterone. 30292827 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 Biomarker disease PSYGENET The aim of the present study was to examine the role of dopamine D3 receptor on the anxiety-like and depression-like behaviors induced by immobilization stress. 23357086 2013
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 Biomarker disease PSYGENET Direct associations were identified between the dopamine receptor 3 (DRD3) BalI polymorphism and depression; the dopamine receptor 1 (DRD1) and dopamine transporter gene 3' VNTR polymorphisms and aberrant motor behavior; the DRD4 VNTR and sleep disturbances; and the SERT gene VNTR 5HTTLPR and apathy items. 20685009 2012
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 GeneticVariation disease BEFREE Direct associations were identified between the dopamine receptor 3 (DRD3) BalI polymorphism and depression; the dopamine receptor 1 (DRD1) and dopamine transporter gene 3' VNTR polymorphisms and aberrant motor behavior; the DRD4 VNTR and sleep disturbances; and the SERT gene VNTR 5HTTLPR and apathy items. 20685009 2012
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 Biomarker disease PSYGENET Six genes were identified as of interest for a follow-up, based on the strength of the association and based on the interest as potential candidate target for developing new treatment for depression: Solute Carrier Family 4 Member 10 (SLC4A10), Dipeptidyl Peptidase IV (DPP4), Dopamine Receptor D3 (DRD3), Zinc Finger Protein 80 (ZNF80), Nitric Oxide Synthase 2A (NOS2A) and Peroxisome Proliferator-Activated Receptor-Gamma, Coactivator 1, Alpha (PPARGC1A). 21630437 2011
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 Biomarker disease BEFREE Six genes were identified as of interest for a follow-up, based on the strength of the association and based on the interest as potential candidate target for developing new treatment for depression: Solute Carrier Family 4 Member 10 (SLC4A10), Dipeptidyl Peptidase IV (DPP4), Dopamine Receptor D3 (DRD3), Zinc Finger Protein 80 (ZNF80), Nitric Oxide Synthase 2A (NOS2A) and Peroxisome Proliferator-Activated Receptor-Gamma, Coactivator 1, Alpha (PPARGC1A). 21630437 2011
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 Biomarker disease PSYGENET Associations were revealed between DRD3 and elation, and between DRD4 with agitation/aggression and with depression; however, these findings do not remain significant after correction for multiple testing. 19235789 2009
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 Biomarker disease BEFREE Associations were revealed between DRD3 and elation, and between DRD4 with agitation/aggression and with depression; however, these findings do not remain significant after correction for multiple testing. 19235789 2009
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 GeneticVariation disease BEFREE Depression and psychotic symptoms that occur in a large proportion of AD patients have been associated with monoamine genes coding for metabolic enzymes (COMT), transporters (5-HTTLPR) and receptors (DRD1; DRD3). 17851196 2007
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.360 Biomarker disease PSYGENET Depression and psychotic symptoms that occur in a large proportion of AD patients have been associated with monoamine genes coding for metabolic enzymes (COMT), transporters (5-HTTLPR) and receptors (DRD1; DRD3). 17851196 2007