DUSP5, dual specificity phosphatase 5, 1847

N. diseases: 78; N. variants: 2
Disease: Cardiomyopathy, Familial Idiopathic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1449563
Disease: Cardiomyopathy, Familial Idiopathic
Cardiomyopathy, Familial Idiopathic 		0.010 AlteredExpression disease BEFREE These findings suggest that diabetes-activated HDAC3 inhibits DUSP5 expression through deacetylating histone H3 on the primer region of <i>DUSP5</i> gene, leading to the derepression of ERK1/2 and the initiation of DCM. 28533215 2017