AGTR1, angiotensin II receptor type 1, 185

N. diseases: 440; N. variants: 33
Disease: Malignant Hypertension ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020540
Disease: Malignant Hypertension
Malignant Hypertension 		0.030 GeneticVariation disease BEFREE Angiotensin II type 1 receptor autoantibodies (AT<sub>1</sub>R-AAs) are known to be associated with malignant hypertension, preeclampsia, and vascular rejection in kidney transplantation. 28004166 2017
CUI: C0020540
Disease: Malignant Hypertension
Malignant Hypertension 		0.030 Biomarker disease BEFREE The autoantibodies (AAs) against angiotensin AT(1) receptors (AT(1) -AAs) have been discovered in patients with preeclampsia, malignant hypertension, and essential hypertension (EH); however, the mechanism of AA production remains to be investigated. 21557256 2011
CUI: C0020540
Disease: Malignant Hypertension
Malignant Hypertension 		0.030 Biomarker disease BEFREE Activating antibodies targeting the AT1R were detected in the sera from 14 SRAR victims with malignant hypertension and without anti-HLA antibodies. 17984617 2007