S1PR3, sphingosine-1-phosphate receptor 3, 1903

N. diseases: 47; N. variants: 2
Disease: OVERLAP CONNECTIVE TISSUE DISEASE ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1858556
Disease: OVERLAP CONNECTIVE TISSUE DISEASE
OVERLAP CONNECTIVE TISSUE DISEASE 		0.010 AlteredExpression disease BEFREE Moreover, S1pr3, encoding one of the five known S1P receptors (S1P3), was found differentially expressed in osteoblasts, and S1P3 deficiency corrected the moderate high bone mass phenotype of a mouse model (deficient for the calcitonin receptor) with increased S1P release from osteoclasts. 31314788 2019