Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.030 Biomarker group BEFREE The star-POEGMA polymers were nontoxic to normal cells and delivered siRNA with high efficiency to pancreatic cancer cells to silence a gene (TUBB3/βIII-tubulin) which is currently undruggable using chemical agents, and is involved in regulating tumor growth and metastases. 27305597 2016
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.030 Biomarker group BEFREE Finally, we assessed the role of βIII-tubulin in regulating tumor growth and metastases using an orthotopic pancreatic cancer mouse model. 25544769 2015
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.030 AlteredExpression group BEFREE Among these neuronal predominant markers, in silico analysis revealed overexpression of βIII-tubulin (TUBB3) in breast cancer brain metastases (BCBM) and its expression was significantly associated with distant metastases. 25724666 2015