|
Schizophrenia
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
Association of EPHB1 rs11918092 and EFNB2 rs9520087 with psychopathological symptoms of schizophrenia in Chinese Zhuang and Han populations.
|
27028544 |
2016 |
|
Schizophrenia
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
In the previous study, we provided evidence for a significant association between the EFNB2 gene and schizophrenia in Han Chinese subjects.
|
27650867 |
2016 |
|
Schizophrenia
|
0.330 |
Biomarker
|
disease |
BEFREE |
Overall our findings indicate that EFNB2 gene may be a candidate susceptibility gene for schizophrenia in the Han Chinese population, and also provide further support for the potential importance of the NMDA receptor pathway in the etiology of schizophrenia.
|
20483485 |
2010 |
|
Schizophrenia
|
0.330 |
Biomarker
|
disease |
PSYGENET |
Overall our findings indicate that EFNB2 gene may be a candidate susceptibility gene for schizophrenia in the Han Chinese population, and also provide further support for the potential importance of the NMDA receptor pathway in the etiology of schizophrenia.
|
20483485 |
2010 |
|
Liver neoplasms
|
0.310 |
Biomarker
|
group |
CTD_human |
Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.
|
19233941 |
2009 |
|
Liver neoplasms
|
0.310 |
Biomarker
|
group |
BEFREE |
Expression of receptor tyrosine kinase HTK (hepatoma transmembrane kinase) and HTK ligand by human leukemia-lymphoma cell lines.
|
10221518 |
1999 |
|
Congenital absence of lung
|
0.300 |
Therapeutic
|
disease |
CTD_human |
Upregulated EFNB2 and EPHB4 promotes lung development in a nitrofen-induced congenital diaphragmatic hernia rat model.
|
30106123 |
2018 |
|
Primary pulmonary hypoplasia
|
0.300 |
Therapeutic
|
disease |
CTD_human |
Upregulated EFNB2 and EPHB4 promotes lung development in a nitrofen-induced congenital diaphragmatic hernia rat model.
|
30106123 |
2018 |
|
Unilateral lung agenesis
|
0.300 |
Therapeutic
|
disease |
CTD_human |
Upregulated EFNB2 and EPHB4 promotes lung development in a nitrofen-induced congenital diaphragmatic hernia rat model.
|
30106123 |
2018 |
|
Unilateral lobar pulmonary agenesis
|
0.300 |
Therapeutic
|
disease |
CTD_human |
Upregulated EFNB2 and EPHB4 promotes lung development in a nitrofen-induced congenital diaphragmatic hernia rat model.
|
30106123 |
2018 |
|
Lung Neoplasms
|
0.300 |
Biomarker
|
group |
CTD_human |
Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents.
|
27935865 |
2017 |
|
Malignant neoplasm of lung
|
0.300 |
Biomarker
|
disease |
CTD_human |
Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents.
|
27935865 |
2017 |
|
Precancerous Conditions
|
0.300 |
Biomarker
|
group |
CTD_human |
Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.
|
19233941 |
2009 |
|
Condition, Preneoplastic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.
|
19233941 |
2009 |
|
Malignant neoplasm of liver
|
0.300 |
Biomarker
|
disease |
CTD_human |
Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.
|
19233941 |
2009 |
|
Reperfusion Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
Effect of furosemide infusion on renal hemodynamics and angiogenesis gene expression in acute renal ischemia/reperfusion.
|
16526316 |
2006 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Overall, our study is the first to implicate the role of EphB4-ephrin-B2 in tumor immune response.
|
30894369 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
We confirmed by immunostaining that EphB4-positive cells existing only in the tumor core, whereas ephrin-B2-positive cells widespread in both the tumor core and the invasive area signifying that EphB4-ephrin-B2 reaction occurred only at the tumor core.
|
30776480 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
We detected that CRABP1, Nestin, and Ephrin B2 are expressed in the intratumoural stroma as well as the tumour invasive front of skin tumours of appendages and BCCs.
|
31065284 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The tumor-cell activated phenotype of EPC was associated with increased migration and elevated expression of ephrin-B2, and Delta-like 4 ligand (DLL4).
|
30205087 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Ephrin-B2 protein expression was associated with tumor size (P<0.001), metastasis (P=0.02) and TNM stage (P=0.03), and was indicated to be an independent prognostic factor for gastric cancer.
|
30214580 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In HNSCC patients, high-EFNB2 mRNA expression was associated with tumor HPV negativity, oral cavity location, alcohol intake, higher TP53 mutation, and EGFR amplification.
|
27649287 |
2017 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
These results suggest that ephrin-B2 overexpression and activation of the ephrin-B2 reverse signaling pathway in tumor microenvironment in OSCC facilitates progression and lymph node metastasis via enhancement of malignant potential and interaction with surrounding cells.
|
29190834 |
2017 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Tumor associated endothelial cells (TAECs) exposed to LPA demonstrated sustained nuclear PKD-1 phosphorylation, and elevated mRNA levels of ephrin B2, and reduced mRNA expression of CD36.
|
28186980 |
2017 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
In vitro cell line and in vivo nude mice data show that EFNB2 silencing restores chemosensitivity in mutant p53-harboring tumors.
|
26494468 |
2016 |