EGFR, epidermal growth factor receptor, 1956

N. diseases: 1394; N. variants: 183
Disease: Dermatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011603
Disease: Dermatitis
Dermatitis 		0.330 Biomarker disease BEFREE Superoxide dismutase 3 inhibits LL-37/KLK-5-mediated skin inflammation through modulation of EGFR and associated inflammatory cascades. 31465746 2020
CUI: C0011603
Disease: Dermatitis
Dermatitis 		0.330 Biomarker disease CTD_human In addition, EGF (rs10029654), EGFR (rs12718939), CXCL12 (rs197452), and VCAM1 (rs3917018) genes showed an association with hand dermatitis (P < 0.005). 27206134 2016
CUI: C0011603
Disease: Dermatitis
Dermatitis 		0.330 Biomarker disease BEFREE The epidermal growth factor receptor (EGFR) plays a key role in skin inflammation, wound healing, and carcinogenesis. 26194695 2015
CUI: C0011603
Disease: Dermatitis
Dermatitis 		0.330 Biomarker disease BEFREE Mice lacking epidermal EGFR (EGFR(Δep)) show a similar phenotype, which is accompanied by chemokine-driven skin inflammation, hair follicle degeneration, decreased host defense, and deficient skin barrier function, as well as early lethality. 23966300 2013