EGFR, epidermal growth factor receptor, 1956

N. diseases: 1394; N. variants: 183
Disease: Dermatologic disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders 		0.040 Biomarker group BEFREE These findings suggested that the TNF-α-induced EGFR transactivation pathway could be a target for the treatment of inflammatory skin diseases. 29279286 2018
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders 		0.040 GeneticVariation group BEFREE Skin conditions are the most common toxicities associated with EGFR inhibitors, particularly papulopustular rash. 28477738 2017
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders 		0.040 Biomarker group BEFREE Exoming into rare skin disease: EGFR deficiency. 25219648 2014
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders 		0.040 Biomarker group BEFREE Although previous reports have shown that cutaneous manifestations are triggered by the inhibition of multiple EGFR-related homeostatic functions of the skin, this mechanism alone cannot explain the differences in frequency and severity of skin disorders caused by different kinase inhibitors. 21606217 2011