EGFR, epidermal growth factor receptor, 1956

N. diseases: 1394; N. variants: 183
Disease: Acute respiratory failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0264490
Disease: Acute respiratory failure
Acute respiratory failure 		0.020 AlteredExpression disease BEFREE We previously demonstrated that wild type and mutant EGFRs repress the expression of the ARF tumor suppressor to promote the survival of lung tumor cells. 29959911 2018
CUI: C0264490
Disease: Acute respiratory failure
Acute respiratory failure 		0.020 AlteredExpression disease BEFREE These findings identify the Arf tumor suppressor as a new transcriptional target of nuclear EGFR and highlight Vps34 as an important regulator of the nuclear EGFR/Arf survival pathway. 26686095 2016