EPHA2, EPH receptor A2, 1969

N. diseases: 187; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 Biomarker disease BEFREE Importantly, the coactivation of EphA2 and YAP is manifested in clinical human GC, and is related to GC recurrence. 31376289 2020
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 AlteredExpression disease BEFREE <b>Conclusions:</b> The expression of miR-302b and EphA2 was inversely correlated, and had prognostic significance on GC in clinic. 30210634 2018
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 Biomarker disease BEFREE We previously reported that EphA2 promotes the epithelial-mesenchymal transition through Wnt/β-catenin signaling in gastric cancer. 30451837 2018
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 Biomarker disease BEFREE This modulation of EphA2 also had distinct effects on cell proliferation and migration in GC in vivo. 29273006 2017
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 AlteredExpression disease BEFREE Proliferation index (PI) was significantly upregulated following an increase in EphA2 expression in gastric carcinoma compared with dysplasia and normal samples, and was notably correlated with grade and lymph node metastasis. 25310629 2014
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 AlteredExpression disease BEFREE Subgroup analysis also indicated a significant relation between EphA2 overexpression and OS in gastric cancer (HR: 1.95, 95% CI: 1.48-2.59). 25418013 2014
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 PosttranslationalModification disease BEFREE The biological function of miR-520d-3p in GC cells was investigated using a methylthiazolyldiphenyl-tetrazolium bromide assay, cell cycle assay, transwell invasion assay, and wound-healing assay. miR-520d-3p expression was down-regulated and inversely correlated with the expression of EphA2 in GC tissues and cell lines. 25063221 2014