ELANE, elastase, neutrophil expressed, 1991

N. diseases: 346; N. variants: 33
Disease: Colitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009319
Disease: Colitis
Colitis 		0.030 Biomarker disease BEFREE Faecal neutrophil elastase-antiprotease balance reflects colitis severity. 31772324 2020
CUI: C0009319
Disease: Colitis
Colitis 		0.030 AlteredExpression disease BEFREE Thus, PK105b facilitates detection of neutrophil elastase activity in tissue lysates, and we have applied it to demonstrate that this protease is unequivocally activated during colitis. 31527638 2019
CUI: C0009319
Disease: Colitis
Colitis 		0.030 Biomarker disease BEFREE In mice given TNBS or DSS, transgenic expression of elafin or disruption of NE and PR-3 protected against the development of colitis. 21199654 2011